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FAM114A1
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FAM114A1 : ウィキペディア英語版
FAM114A1

Protein FAM114A1 also known as nervous system overexpressed protein 20 (NOXP20) is a protein that in humans is encoded by the FAM114A1 gene.〔(【引用サイトリンク】sapiens )">url=http://www.ncbi.nlm.nih.gov/nuccore/NM_138389.2 )〕 Orthologs of FAM114A1 reach as far back in evolution to ''Drosophila'', however, it's closer in homology to primates than any other orthologs. FAM114A1 has one paralog, FAM114A2, which also encodes a protein of unknown function.
== Gene ==
FAM114A1 is located on the short arm of Chromosome 4 (4.p14) in humans on the forward strand sense, it starts at base pair 38869354 and ends at 38947365.〔 Its mRNA has 4138 bp. The gene has the following neighbors on the same chromosome:

:TLR1: Toll-like receptor (TLR) 1 plays a role in pathogen recognition and activation of innate immunity.
:TLR6: Toll-like receptor (TLR) 6 plays a role in pathogen recognition and activation of innate immunity.
:TMEM156: The gene codes for a transmembrane protein.
:KLHL5: Kelch-like 5, its protein is thought to have a role in lymphocyte activation.〔(【引用サイトリンク】url=http://www.genecards.org/cgi-bin/carddisp.pl?gene=KLHL5 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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