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FAM136A
Family with sequence similarity 163, Member A (FAM163A) is a protein encoded by a gene of the same name. Common aliases for this protein are: RP11-12M5.2, C1orf146, Neuroblastoma-Derived Secretory Protein (NDSP), and Cebelin. While its function is not yet completely understood, this protein has been implicated in promoting proliferation and anchorage-independent growth of neuroblastoma cancer cells. In addition, this protein has been found to be up-regulated in the lung tissue of chronic smokers. ''FAM163A'' is found on human chromosome 1q25.2; its protein product is 167 amino acids long. FAM163A contains a very highly conserved signal peptide sequence, coded for by the first ~37 amino acids in its sequence; albeit only conserved in eukaryotes, the most distant of which being the Japanese Rice Fish. == Clinical significance == Mutations in FAM136A are associated to .
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「FAM136A」の詳細全文を読む
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