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FAM162A
Human growth and transformation-dependent protein (HGTD-P), also called E2-induced gene 5 protein (E2IG5), is a protein that in humans is encoded by the ''FAM162A'' gene on chromosome 3. This protein promotes intrinsic apoptosis in response to hypoxia via interactions with hypoxia-inducible factor-1α (HIF-1α).〔 As a result, it has been associated with cerebral ischemia, myocardial infarction, and various cancers.〔 ==Structure==
HGTD-P contains two transmembrane domains that are required for its localization to the mitochondria and induction of cell death.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「FAM162A」の詳細全文を読む
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