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FAM71D, also known as chromosome 14 open reading frame 54 (C14orf54), is a protein that in humans is encoded by the FAM71D gene on Chromosome 14. Orthologs of FAM71D reach as far back in evolution to ''Reptiles'', however, it is closer in homology to primates than any other orthologs. FAM71D has 6 paralogs: FAM71A, FAM71B, FAM71C, FAM71E1, FAM71F1, FAM71F2 which encode a protein of unknown function. ==Gene== In humans, FAM71D is located at 14q23.3 and stretches between positions 67189393 and 67228550 (span 39157 bp). It codes for at least 10 unique human protein isoforms: the primary isoform (422 aa; also denoted X1), isoform X2 (417 aa), isoform X3 (413 aa), isoform X4 (400 aa), isoform X5 (399 aa), isoform X6 (398 aa), isoform X7 (392 aa), isoform X8 (389 aa), isoform X9 (347 aa), isoform X10 (336 aa) In humans, FAM71D codes for an mRNA strand that is 1790 base pairs long. The human mRNA is composed of a 5' untranslated region that is 290 bases long and a 3' untranslated region that is 231 bases long The gene has the following neighbors on the same chromosome: :MPP5: MAGUK p55 subfamily member 5 plays a role in tumor suppression and receptor clustering :GPHN: Gephyrin plays a role in anchoring inhibitory neurotransmitter receptors to postsynaptic cytoskeleton :AT6V1D: V-type proton ATPase subunit D, an ezyme that mediates acidifcation of eukaryotic intracellular organelles :SF3B44P1: Splicing Factor 3b, Subunit 4 Pseudogene 1 :LOC101927920: Probable Ribosome Biogenesis Protein RLP24-Like :LOC105370538: Uncharacterized protein :LOC105370541: Uncharacterized protein File:Gene Neighbors.png 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「FAM71D」の詳細全文を読む スポンサード リンク
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