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FAM73B
family with sequence similarity 73, member B, also known as FAM73B, is a human gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=84895 )〕 ==Model organisms==
Model organisms have been used in the study of FAM73B function. A conditional knockout mouse line, called ''Fam73btm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty four tests were carried out on mutant mice and six significant abnormalities were observed. Homozygous mutant animals had a decreased body weight, altered body composition, abnormal tooth morphology, hypoalbuminemia, decreased bone mineral content and strength, and an increased susceptibility to bacterial infection.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「FAM73B」の詳細全文を読む
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