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FARP2
FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the ''FARP2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9855 )〕 == Model organisms ==
Model organisms have been used in the study of FARP2 function. A conditional knockout mouse line, called ''Farp2tm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty four tests were carried out on mutant mice and two significant abnormalities were observed.〔 Homozygous mutant animals had a thickened cerebral cortex and displayed abnormal hair shedding.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「FARP2」の詳細全文を読む
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