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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク FGFR1OP2 ： ウィキペディア英語版 FGFR1OP2 Fibroblast growth factor receptor oncogene partner 2 (FGFR1OP2) was identified in a study on myeloproliferative syndrome (EMS). The study aimed to identify the partner genes to the fibroblast growth factor receptor 1 (FGFR1) involved in the syndrome. Using the 5'-RACE PCR technique, FGFR1OP2 was identified as a novel gene with no known function. == Function == FGFR1OP2, when fused with the fibroblast growth factor receptor 1 (FGFR1), is shown to cause myeloproliferative syndrome.〔 The protein encoded by the FGFR1 gene belongs to the fibroblast growth factor receptor family. FGFRs usually contain an extracellular ligand binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain, and the extracellular domain specifies which ligand the receptor will bind to and mediates ligand-induced receptor dimerization. When FGFR1OP2 is fused to FGFR1, it may exhibit constitutive kinase activity.〔(【引用サイトリンク】title=''FGFR1OP2'' )〕 Furthermore, FGFR1OP2 is possibly involved in some steps of the wound healing pathway.〔(【引用サイトリンク】title=''FGFR1OP2'' )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「FGFR1OP2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.