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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク FNDC5 ： ウィキペディア英語版 FNDC5 Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. Fibronectin domain-containing protein 5 is a membrane protein comprising a short cytoplasmic domain, a transmembrane segment, and an ectodomain consisting of a ~100 kDa fibronectin type III (FNIII) domain. The ectodomain has been proposed to be cleaved to give a soluble peptide hormone named irisin. It has been proposed that irisin is secreted from muscle in response to exercise, and may mediate some beneficial effects of exercise in humans and the potential for generating weight loss and blocking diabetes has been suggested. while others have questioned these findings.〔 == Discovery == FNDC5 was initially discovered during a genome search for fibronectin type III domains and also independently in a search for peroxisomal proteins.〔 Irisin was found to be a cleaved version of FNDC5. The cleaved product has been called irisin, after the Greek messenger goddess Iris.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「FNDC5」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.