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FOLFOX is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs * FOL– Folinic acid (leucovorin) * F – Fluorouracil (5-FU) * OX – Oxaliplatin (Eloxatin)〔(Cancer Research UK, CancerHelp UK )〕 == FOLFOX4 == Adjuvant treatment in patients with stage III colon cancer is recommended for 12 cycles, every 2 weeks. The recommended dose schedule given every two weeks is as follows: Day 1: Oxaliplatin 85 mg/m² IV infusion in 250-500 mL D5W and leucovorin 200 mg/m² IV infusion in D5W both given over 120 minutes at the same time in separate bags using a Y-line, followed by 5-FU 400 mg/m² IV bolus given over 2–4 minutes, followed by 5-FU 600 mg/m² IV infusion in 500 mL D5W (recommended) as a 22-hour continuous infusion. Day 2: Leucovorin 200 mg/m² IV infusion over 120 minutes, followed by 5-FU 400 mg/m² IV bolus given over 2–4 minutes, followed by 5-FU 600 mg/m² IV infusion in 500 mL D5W (recommended) as a 22-hour continuous infusion. Premedication with antiemetics, including 5-HT3 blockers with or without dexamethasone, is recommended. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「FOLFOX」の詳細全文を読む スポンサード リンク
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