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FOXA2 : ウィキペディア英語版
FOXA2

Hepatocyte nuclear factor 3-beta (HNF-3B), also known as forkhead box protein A2 (FOXA2) or transcription factor 3B (TCF-3B) is a protein that in humans is encoded by the ''FOXA2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3170 )
== Function ==

Forkhead box protein A2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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