翻訳と辞書 Words near each other ・ Foxite ・ FOXJ1 ・ FOXJ2 ・ Foxjet ST600 ・ FOXK1 ・ FOXK2 ・ Foxlease ・ Foxleigh ・ Foxleigh coal mine ・ Foxley ・ Foxley (disambiguation) ・ Foxley (surname) ・ Foxley River, Prince Edward Island ・ Foxley Wood ・ Foxley Wood, Purley ・ FOXM1 ・ Foxmail ・ Foxman ・ Foxmask ・ FOXN1 ・ FOXN3 ・ Foxnet ・ FOXO1 ・ FOXO3 ・ FOXO4 ・ Foxon Park ・ FOXP1 ・ FOXP2 ・ FOXP3 ・ FOXP4 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク FOXM1 ： ウィキペディア英語版 FOXM1 Forkhead box protein M1 is a protein that in humans is encoded by the ''FOXM1'' gene. The protein encoded by this gene is a member of the FOX family of transcription factors.〔〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2305 )〕 FOXM1 has been awarded the Molecule of the Year 2010 for its growing potential as a target for cancer diagnosis and therapies. == Function == FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. FOXM1-null mouse embryos were neonatal lethal as a result of the development of polyploid cardiomyocytes and hepatocytes, highlighting the role of FOXM1 in mitotic division. More recently a study using transgenic/knockout mouse embryonic fibroblasts and human osteosarcoma cells (U2OS) has shown that FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「FOXM1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.