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Flucloxacillin
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Flucloxacillin : ウィキペディア英語版
Flucloxacillin

Flucloxacillin (INN) or floxacillin (USAN) is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. Unlike other penicillins, flucloxacillin has activity against beta-lactamase-producing organisms such as ''Staphylococcus aureus'' as it is beta-lactamase stable. However, it is ineffective against methicillin-resistant Staphylococcus aureus (MRSA).〔(NHS: Methicillin-resistant Staphylococcus aureus (MRSA) - Guidance for nursing staff ) "methicillin resistance means the same as flucloxacillin resistance"〕 It is very similar to dicloxacillin; they are considered interchangeable. While no longer used in the United States, Flucloxacillin is supplied under a variety of trade names, including Floxapen (Beecham, now GSK), Flopen (CSL), Staphylex (Alphapharm), Softapen (Rephco Pharmaceuticals Limited), and Flubex (Beximco Pharmaceuticals Ltd, Bangladesh).
==Overview of common uses==
It is most commonly used to treat infections such as:
*Chest, ear, nose and throat (e.g. tonsillitis, sinusitis, pneumonia)
*Skin and soft tissue (e.g. boils, burns, wounds, abscesses, infected eczema, infected acne)
*Other infections including those of the heart (endocarditis), bones and joints (osteomyelitis), membranes of the brain (meningitis), guts (enteritis), blood (septicaemia), and the kidney, bladder or urethra
Flucloxacillin can also be used to prevent infections during major surgical procedures, particularly in heart or orthopedic surgery.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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