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Fluoxetine : ウィキペディア英語版
Fluoxetine


Fluoxetine, also known by trade names including Prozac and Sarafem among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine was discovered and developed by scientists from Eli Lilly and Company.〔 It was approved by the U.S. Food and Drug Administration for the treatment of major depressive disorder in December 1987. The U.S. fluoxetine patent expired in August 2001, so generic formulations are now available in the U.S.
Fluoxetine is used for the treatment of major depressive disorder (including pediatric depression), obsessive–compulsive disorder (in both adults and children), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. In addition, it is used to treat trichotillomania if cognitive behaviour therapy has been unsuccessful.

In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States, making it the third-most prescribed antidepressant after sertraline and citalopram.〔 In 2011, 6 million prescriptions for fluoxetine were filled in the United Kingdom. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
==Medical uses==

Fluoxetine is frequently used to treat major depressive disorder, obsessive-compulsive disorder, post-traumatic stress disorder, bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.〔〔Truven Health Analytics, Inc. DrugPoint® System (Internet) (2013 Oct 4 ). Greenwood Village, CO: Thomsen Healthcare; 2013.〕〔Australian Medicines Handbook 2013. The Australian Medicines Handbook Unit Trust; 2013.〕〔British National Formulary (BNF) 65. Pharmaceutical Pr; 2013.〕 It has also been used for cataplexy, obesity, and alcohol dependence,〔(【引用サイトリンク】url=http://www.drugs.com/monograph/fluoxetine-hydrochloride.html )〕 as well as binge eating disorder. It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Fluoxetine」の詳細全文を読む



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