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・ Foje
・ Fojhar
・ Foji Gill
・ Fojia
・ Fojnica
・ Fojnica (disambiguation)
・ Fojnica Armorial
・ Fojnica, Gacko
・ Fojnička rijeka
・ Fojutowo
・ FOK
・ Fok
・ FOK!
・ Fokas
・ Fokestar
FokI
・ Fokienia
・ Fokikos A.C.
・ Fokin
・ Fokin Government
・ Fokino
・ Fokino (inhabited locality)
・ Fokino Urban Okrug
・ Fokino, Bryansk Oblast
・ Fokino, Primorsky Krai
・ Fokke & Sukke
・ Fokker
・ Fokker (disambiguation)
・ Fokker 100
・ Fokker 50


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FokI : ウィキペディア英語版
FokI

The enzyme FokI, naturally found in ''Flavobacterium okeanokoites'', is a bacterial type IIS restriction endonuclease consisting of an N-terminal DNA-binding domain and a non-specific DNA cleavage domain at the C-terminal. Once the protein is bound to duplex DNA via its DNA-binding domain at the 5'-GGATG-3' recognition site, the DNA cleavage domain is activated and cleaves, without further sequence specificity, the first strand 9 nucleotides downstream and the second strand 13 nucleotides upstream of the nearest nucleotide of the recognition site.
Its molecular mass is 65.4 kDa, being composed of 587 amino acids.
== DNA-binding domain ==

The recognition domain contains three subdomains (D1, D2 and D3) that are evolutionarily related to the DNA-binding domain of the catabolite gene activator protein which contains a helix-turn-helix.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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