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Formate
Formate (IUPAC name: methanoate) is the anion derived from formic acid. Its formula is represented in various equivalent ways: CHOO− or HCOO− or HCO2−. It is the product of deprotonation of formic acid. It is the simplest carboxylate anion. A formate (compound) is a salt or ester of formic acid. ==Biochemistry== Formate is produced in large amounts in the hepatic (liver cells) mitochondria of embryonic cells and in cancer cells by the folate cycle.〔H Frederik Nijhout, et al, In silico experimentation with a model of hepatic mitochondrial folate metabolism, Theoretical Biology and Medical Modeling, 2006, 3:40, link http://www.tbiomed.com/content/3/1/40/abstract).〕 Formate is reversibly oxidized by the enzyme formate dehydrogenase:〔T. Reda, C. M. Plugge, N. J. Abram and J. Hirst, "Reversible interconversion of carbon dioxide and formate by an electroactive enzyme", PNAS 2008 105, 10654–10658. 〕 :HCO2− → CO2 + H+ + 2 e−
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