翻訳と辞書 Words near each other ・ Fraissines ・ Fraissinet-de-Fourques ・ Fraissinet-de-Lozère ・ Fraissé-des-Corbières ・ Fraisthorpe ・ Fraita ・ Fraize ・ Fraizer ・ Fraizer Campbell ・ Fraj Bnouni ・ Frajhajm ・ Frak ・ FRAK (engine) ・ Frak (expletive) ・ Frak! ・ Frakefamide ・ Frakes ・ Frakes Aviation ・ Frakes, Kentucky ・ Frakk ・ Fraktal ・ Fraktur ・ Fraktur (disambiguation) ・ Fraktur (folk art) ・ Frakull ・ Frakull e Madhe ・ Fraley ・ Fraley (surname) ・ Fraley Island ・ Fraley Rogers Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Frakefamide ： ウィキペディア英語版 Frakefamide Frakefamide (INN) is a synthetic, fluorinated opioid tetrapeptide with the amino acid sequence Tyr-D-Ala-(''p''-F)Phe-Phe-NH2 which acts as a peripherally-specific, selective μ-opioid receptor agonist. Despite its inability to penetrate the blood-brain-barrier and enter the central nervous system,〔 frakefamide has potent analgesic effects and, unlike centrally-acting opioids like morphine, does not produce respiratory depression, indicating that its antinociceptive effects are mediated by peripheral μ-opioid receptors.〔 It was under development for the treatment of pain by AstraZeneca and Shire but was shelved after phase II clinical trials. == See also == * Casokefamide * Metkefamide 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Frakefamide」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.