翻訳と辞書 Words near each other ・ Frucor ・ Frucourt ・ FRUCT ・ Fructan ・ Fructan beta-(2,1)-fructosidase ・ Fructan beta-(2,6)-fructosidase ・ Fructan beta-fructosidase ・ Fructidor ・ Fructification ・ Fructokinase ・ Fructolysis ・ Fructone ・ Fructooligosaccharide ・ Fructosamine ・ Fructosamine kinase family ・ Fructosamine-3-kinase ・ Fructose ・ Fructose 1,6-bisphosphatase ・ Fructose 1,6-bisphosphate ・ Fructose 1-phosphate ・ Fructose 2,6-bisphosphate ・ Fructose 5-dehydrogenase ・ Fructose 5-dehydrogenase (NADP+) ・ Fructose 6-phosphate ・ Fructose bisphosphatase ・ Fructose bisphosphatase deficiency ・ Fructose intolerance (disambiguation) ・ Fructose malabsorption ・ Fructose-2,6-bisphosphate 2-phosphatase ・ Fructose-2,6-bisphosphate 6-phosphatase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Fructosamine-3-kinase ： ウィキペディア英語版 Fructosamine-3-kinase Fructosamine-3-kinase is an enzyme that in humans is encoded by the ''FN3K'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64122 )〕 ==Function== FN3K catalyzes phosphorylation of fructosamines formed by glycation, the nonenzymatic reaction of glucose with primary amines followed by Amadori rearrangement. Phosphorylation of fructosamines may initiate metabolism of the modified amine and result in deglycation of glycated proteins.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64122 )〕 FN3K is responsible for the formation of fructose 3-phosphate (F3P), a compound identified in the lenses of diabetic rats. The spontaneous decomposition of F3P leads to the formation of 3-deoxyglucosone (3DG). 3DG contributes to diabetic complications. Treatment of normal and diabetic rats with an inhibitor of FN3K demonstrated a large reduction (~50%) in systemic 3DG in both groups. Removal of 3DG at its source by inhibition of FN3K is a viable option to treat diabetes related diseases since it would require a much smaller dose of drug. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Fructosamine-3-kinase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.