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GAPVD1
GTPase activating protein and VPS9 domains 1, also known as GAPVD1, Gapex-5 and RME-6 is a protein which in humans is encoded by the ''GAPVD1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26130 )〕 == Function ==
GAPVD1 is Rab ''GTPase'' guanine nucleotide exchange factor essential for activation of RAB5A during engulfment of apoptotic cells. GAPVD1 is also involved in the degradation of the epidermal growth factor receptor. Gapex-5 mediated activation of Rab5 has been implicated in the insulin stimulated formation of plasma membrane phosphatidylinositol-3-phosphate.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「GAPVD1」の詳細全文を読む
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