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・ Gliese 3634
・ Gliese 3634 b
・ Gliese 3685 A
・ Gliese 393
・ Gliese 402
・ Gliese 408
・ Gliese 412
・ Gliese 42
・ Gliese 422 b
・ Gliese 433
・ Glibaći
・ Glibenclamide
・ Glibness
・ Glibornuride
・ Glibovac
GLIC
・ Glicaramide
・ Gliceria Marella Villavicencio
・ Glichów
・ Glick
・ Glick-Orr House
・ Glick-Sower House
・ Glickman
・ Glicko
・ Glicko rating system
・ Glicksberg's theorem
・ Gliclazide
・ Glico Morinaga case
・ Glicourt
・ Gliczarów Dolny


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GLIC : ウィキペディア英語版
GLIC

The GLIC receptor is a bacterial (Gloeobacter) Ligand-gated Ion Channel, homolog to the nicotinic acetylcholine receptors. It is a proton-gated, cation-selective channel, and like the nicotinic acetylcholine receptors is a functional pentameric oligomer. However while its eukaryotic homologues are hetero-oligomeric, all until now known bactria known to express LICs encode a single monomeric unit, indicating the GLIC to be functionally homo-oligomeric.
The similarity of amino-acid sequence to the eukaryotic LGICs is not localized to any single or particular tertiary domain, indicating the similar function of the GLIC to its euaryotic equivalents. Regardless, the purpose of regulating the threshold for action potential excitation in the nerve signal transmission of multicellular organisms cannot translate to single-cell organisms, thereby not making the purpose of bacterial LGICs immediately obvious.
==Structure==

The structure of the open channel structure was solved by two independent research teams in 2009 at low pH values of 4-4.6 (GLIC being proton-gated).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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