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GPR112
G protein-coupled receptor 112 is a protein encoded by the ''ADGRG4'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=139378 )〕 GPR112 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain. GPR112 is expressed in human enterochromaffin cells and in the mouse intestine. The N-terminal fragment (NTF) of GPR112 contains pentraxin (PTX)-like modules.〔 GPR112 gene expression has been identified as a marker for neuroendocrine carcinoma cells.〔 == References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「GPR112」の詳細全文を読む
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