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GPR119
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GPR119 : ウィキペディア英語版
GPR119

G protein-coupled receptor 119 also known as GPR119 is a G protein-coupled receptor that in humans is encoded by the ''GPR119'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=139760 )
GPR119, along with GPR55 and GPR18, have been implicated as novel cannabinoid receptors.
== Pharmacology ==

GPR119 is expressed predominantly in the pancreas and gastrointestinal tract in rodents and humans, as well as in the brain in rodents. Activation of the receptor has been shown to cause a reduction in food intake and body weight gain in rats.〔 GPR119 has also been shown to regulate incretin and insulin hormone secretion. As a result, new drugs acting on the receptor have been suggested as novel treatments for obesity and diabetes.〔〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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