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GPR77
C5a anaphylatoxin chemotactic receptor C5a2 also known as C5L2, G protein-coupled receptor 77, is a protein that in humans is encoded by the ''C5AR2'' gene.〔 == Function ==
The anaphylatoxins C3a, C4a, and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5a2 is coexpressed with the C5a receptor, (C5a1, C5aR, C5R1, CD88), on polymorphonuclear neutrophils and may modulate C5a1 activity.〔(【引用サイトリンク】 url = http://www.genenames.org/data/hgnc_data.php?hgnc_id=4527 )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「GPR77」の詳細全文を読む
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