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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク GRAP ： ウィキペディア英語版 GRAP GRB2-related adapter protein is a protein that in humans is encoded by the ''GRAP'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10750 )〕 This gene encodes a member of the GRB2/Sem5 (''C. elegans'' homolog)/Drk (''Drosophila'' homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.〔 == Interactions == GRAP has been shown to interact with Linker of activated T cells. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「GRAP」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.