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Words near each other
・ GRB 080916C
・ GRB 090423
・ GRB 090429B
・ GRB 100621A
・ GRB 101225A
・ GRB 110328A
・ GRB 111209A
・ GRB 130427A
・ GRB 790305b
・ GRB 830801
・ GRB 970228
・ GRB 970508
・ GRB 971214
・ GRB 980425
・ GRB 990123
GRB10
・ GRB14
・ GRB2
・ GRB7
・ Grbalj
・ Grbavac, Bjelovar-Bilogora County
・ Grbavce
・ Grbavci (Gradiška)
・ Grbavica
・ Grbavica (Brčko)
・ Grbavica (film)
・ Grbavica (Novi Sad)
・ Grbavica (Sarajevo)
・ Grbavče
・ Grbeši


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GRB10 : ウィキペディア英語版
GRB10

Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the ''GRB10'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2887 )
== Function ==
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors (e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「GRB10」の詳細全文を読む



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