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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク GTPBP3 ： ウィキペディア英語版 GTPBP3 tRNA modification GTPase GTPBP3, mitochondrial is an enzyme that in human is encoded by the ''GTPBP3'' gene on chromosome 19.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84705 )〕 The GTPBP3 gene encodes a GTP-binding protein that is evolutionarily conserved from bacteria to mammals and which is localized to the mitochondrion and functions in tRNA modification.〔 At least two major isoforms due to alternative splicing are known In addition, a polymorphism on valine 250 is known and may influence aminoglydoside-induced deafness.〔 == Structure == The GTPBP3 gene contains 10 exons,〔 and encodes a ~44 kDa GTP-binding protein that is evolutionarily conserved from bacteria to mammals.〔 The N-terminal domain of mitochondrial tRNA modification GTPase mediates the dimerization of the protein in a potassium-independent manner, which is thought to be related to the construction of the binding site for the one-carbon-unit donor in its tRNA modification reaction function.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「GTPBP3」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.