翻訳と辞書 Words near each other ・ GTP ・ GTP cyclohydrolase I ・ GTP cyclohydrolase II ・ GTP cyclohydrolase IIa ・ GTP diphosphokinase ・ GTP' ・ GTP-binding elongation factor family, EF-Tu/EF-1A subfamily ・ GTP-binding protein regulators ・ GTPase ・ GTPase-activating protein ・ GTPase-activator protein for Ras-like GTPase ・ GTPBP1 ・ GTPBP3 ・ GTPBP4 ・ GTPBP6 ・ GTPgammaS ・ GTPlanet ・ GTR ・ GTR (album) ・ GTR (band) ・ GTR 2 – FIA GT Racing Game ・ GTR Euroseries ・ GTR Evolution ・ GTR – FIA GT Racing Game ・ GTR-18 Smokey Sam ・ GTrans ・ Gtranslator ・ GTRE GTX-35VS Kaveri ・ GTRI Advanced Concepts Laboratory ・ GTRI Aerospace, Transportation and Advanced Systems Laboratory Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク GTPgammaS ： ウィキペディア英語版 GTPgammaS |Section2= |Section3= }} GTPgammaS (GTPγS, guanosine 5'-O-()triphosphate) is a non-hydrolyzable or slowly hydrolyzable G-protein-activating analog of guanosine triphosphate (GTP). Many GTP binding proteins demonstrate activity when bound to GTP, and are inactivated via the hydrolysis of the phosphodiester bond that links the γ-phosphate to the remainder of the nucleotide, leaving a bound guanosine diphosphate (GDP) and releasing an inorganic phosphate. This usually occurs rapidly, and the GTP binding protein can then only be activated by exchanging the GDP for a new GTP molecule. The substitution of sulfur for one of the oxygens of the γ-phosphate of GTP creates a nucleotide that either cannot be hydrolyzed or is only slowly hydrolyzed. This prevents the GTP binding proteins from being inactivated, and allows the cellular processes that they carry out when active to be more easily studied. The consequences of the constitutive activation of GTP binding proteins include stimulation of phosphoinositide hydrolysis, cyclic AMP accumulation or elimination, and activation of specific proto-oncogenes. The 35S labelled radioligand of the compound, 35SGTPγS, is used in autoradiography and G-protein binding studies. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「GTPgammaS」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.