翻訳と辞書 Words near each other ・ Galactinol—raffinose galactosyltransferase ・ Galactinol—sucrose galactosyltransferase ・ Galactites ・ Galactites tomentosa ・ Galactitol ・ Galactitol 2-dehydrogenase ・ Galactitol-1-phosphate 5-dehydrogenase ・ Galactocele ・ Galactocentric distance ・ Galactocentrism ・ Galactocerebroside ・ Galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase ・ Galactogen 6beta-galactosyltransferase ・ Galactoglucomannan ・ Galactography ・ Galactokinase ・ Galactokinase deficiency ・ Galactolipase ・ Galactolipid ・ Galactolipid galactosyltransferase ・ Galactolipid O-acyltransferase ・ Galactolysis ・ Galactomannan ・ Galactomyces ・ Galactomyces candidum ・ Galactomyia ・ Galactonate dehydratase ・ Galactonolactone dehydrogenase ・ Galactooligosaccharide ・ Galactophora Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Galactokinase ： ウィキペディア英語版 Galactokinase Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP.〔(【引用サイトリンク】title=galactokinase )〕 Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of β-D-galactose to glucose 1-phosphate.〔 First isolated from mammalian liver, galactokinase has been studied extensively in yeast,〔〔 archaea, plants, and humans.〔 ==Structure== Galactokinase is composed of two domains separated by a large cleft. The two regions are known as the N- and C-terminal domains, and the adenine ring of ATP binds in a hydrophobic pocket located at their interface. The N-terminal domain is marked by five strands of mixed beta-sheet and five alpha-helices, and the C-terminal domain is characterized by two layers of anti-parallel beta-sheets and six alpha-helices.〔 Galactokinase does not belong to the sugar kinase family, but rather to a class of ATP-dependent enzymes known as the GHMP superfamily. GHMP is an abbreviation referring to its original members: galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase. Members of the GHMP superfamily have great three-dimensional similarity despite only ten to 20% sequence identity. These enzymes contain three well-conserved motifs (I, II, and III), the second of which is involved in nucleotide binding and has the sequence Pro-X-X-X-Gly-Leu-X-Ser-Ser-Ala. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Galactokinase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.