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Gardiquimod
Gardiquimod is a selective compound for mouse or human toll-like receptor 7 (TLR7) and acts as an immune response modifier.〔(NCBI: “The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice” )〕〔(NCBI: Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells )〕〔(Nature.com: “Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells” )〕 The core structure is 1H-imidazo()quinoline like in both imiquimod and resiquimod. It is structurally extremely similar to resiquimod differing only by an oxygen for nitrogen switch. ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Gardiquimod」の詳細全文を読む
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