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Gc-MAF Gc-MAF (or Gc protein-derived macrophage activating factor) is an immunomodulatory protein that, by affecting the immune system, may play a role in various diseases.〔 In 2008 claims were made that Gc-MAF can provide a permanent cure for cancer and HIV by activating macrophage white blood cell production. These claims have been the subject of much criticism〔 and are not supported by scientific evidence. The papers supporting the claims have since been retracted by the journals in which they were published. Consumers have been warned about illegal marketing of the substance over the internet.〔 == Description == The full name for Gc-MaF is Gc protein-derived macrophage-activating factor. Biochemically, Gc-MAF results from sequential deglycosylation of the vitamin D-binding protein (the Gc protein), which is naturally promoted by lymphocytes (B and T cells).〔 The resulting protein may be a macrophage activating factor (MAF).〔 MAFs are lymphokines that control the expression of antigens on the surface of macrophages, and one of their functions is to make macrophages become cytotoxic to tumors. Gc-MAF may play a role in various diseases.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Gc-MAF」の詳細全文を読む
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