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GeneCalling
GeneCalling is a mRNA profiling technology finding increased use in the field of genomics and invented by Dr. Jonathan M. Rothberg and developed by ''CuraGen'' Corporation.〔http://www.curagen.com〕 This genomics technique rapidly identifies candidate genes for use in drug discovery and development. Differences between gene expression in healthy tissues and disease or drug responsive tissues are examined and compared in this technology. Novel genes in any organism - most commonly humans, animals, plants and pathogens - as well as known ones, can be detected by this open expression system.
==History==
On February 17, 1999 ''CuraGen'' was granted a patent covering its open architecture system of gene expression technology. The patent was entitled "Method and Apparatus for Identifying, Classifying, or Qualifying DNA Sequences in a Sample Without Sequencing," and covered the newly developed GeneCalling process.〔SeedQuest Press Release, 1999〕 While most methods of analyzing gene expression to this point were closed systems such as ChIP, the open nature of this system was groundbreaking in its provision of greater flexibility through analysis of gene expression without prior sequence information as well as the ability to compare these results to a sequence database.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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