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geWorkbench (genomics Workbench) is an open-source software platform for integrated genomic data analysis. It is a desktop application written in the Java programming language. geWorkbench uses a component architecture. At present, there are more than 70 plug-ins〔http://wiki.c2b2.columbia.edu/workbench/index.php/Plugins〕 available, providing for the visualization and analysis of gene expression, sequence, and structure data. geWorkbench is the Bioinformatics platform of MAGNet,〔http://magnet.c2b2.columbia.edu〕 the National Center for the Multi-scale Analysis of Genomic and Cellular Networks, one of the 8 National Centers for Biomedical Computing〔http://www.ncbcs.org〕 funded through the NIH Roadmap (NIH Common Fund〔http://commonfund.nih.gov/researchteams〕). Many systems and structure biology tools developed by MAGNet investigators are available as geWorkbench plugins. ==Features== * Computational analysis tools such as t-test, hierarchical clustering, self-organizing maps, regulatory network reconstruction, BLAST searches, pattern/motif discovery, protein structure prediction, structure-based protein annotation, etc. * Visualization of gene expression (heatmaps, volcano plot), molecular interaction networks (through Cytoscape), protein sequence and protein structure data (e.g. MarkUs). * Integration of gene and pathway annotation information from curated sources as well as through Gene Ontology enrichment analysis. * Component integration through platform management of inputs and outputs. Among data that can be shared between components are expression datasets, interaction networks, sample and marker (gene) sets and sequences. * Dataset History tracking - complete record of data sets used and input settings. * Integration with 3rd party tools such as Genepattern, Cytoscape and GenomeSpace. Demonstrations of each feature described can be found at http://wiki.c2b2.columbia.edu/workbench/index.php/Tutorials. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Geworkbench」の詳細全文を読む スポンサード リンク
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