翻訳と辞書 Words near each other ・ Glycerol-1-phosphatase ・ Glycerol-2-phosphatase ・ Glycerol-3-phosphate 1-dehydrogenase (NADP+) ・ Glycerol-3-phosphate 2-O-acyltransferase ・ Glycerol-3-phosphate cytidylyltransferase ・ Glycerol-3-phosphate dehydrogenase ・ Glycerol-3-phosphate dehydrogenase (NAD(P)+) ・ Glycerol-3-phosphate dehydrogenase (NAD+) ・ Glycerol-3-phosphate dehydrogenase (quinone) ・ Glycerol-3-phosphate O-acyltransferase ・ Glycerol-3-phosphate oxidase ・ Glycerol-3-phosphate-transporting ATPase ・ Glycerol-3-phosphate—glucose phosphotransferase ・ Glycerolysis ・ Glycerone kinase ・ Glyceroneogenesis ・ Glyceronephosphate O-acyltransferase ・ Glycerophosphocholine cholinephosphodiesterase ・ Glycerophosphocholine phosphodiesterase ・ Glycerophosphodiester phosphodiesterase ・ Glycerophosphoinositol glycerophosphodiesterase ・ Glycerophosphoinositol inositolphosphodiesterase ・ Glycerophospholipid ・ Glycerophospholipid acyltransferase (CoA-dependent) ・ Glycerophospholipid arachidonoyl-transferase (CoA-independent) ・ Glycerophthora ・ Glyceryl behenate ・ Glyceryl hydroxystearate ・ Glycia ・ Glycidic acid Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Glyceroneogenesis ： ウィキペディア英語版 Glyceroneogenesis Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose.〔 〕 Usually glycerol 3-phosphate is generated from glucose by glycolysis, but when glucose concentration drops in the cytosol, it is generated by another pathway called glyceroneogenesis. Glyceroneogenesis uses pyruvate, alanine, glutamine or any substances from the TCA cycle as precursors for glycerol 3-phophate. Phosphoenolpyruvate carboxykinase (PEPC-K),〔 which is an enzyme that catalyses the decarboxylation of oxaloacetate to phosphoenolpyruvate is the main regulator for this pathway. Glyceroneogenesis can be observed in adipose tissue and also liver. It is a significant biochemical pathway which regulates cytosolic lipid levels. Intense suppression of glyceroneogenesis may lead to metabolic disorder such as type 2 diabetes. ==Summary== In mammals, triglycerol or its backbone, glycerol 3- phosphate, is usually synthesized from glucose through glycolysis.〔 Glucose will be degraded though glycolysis until fructose 1,6-bisphosphate is broken down to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Dihydroxyacetone phosphate is significant in synthesizing triglycerides because it can be used to generate glycerol 3-phosphate. However, glycerol 3-phosphate is generated through a different pathway when an organism is deficient of carbohydrates such as glucose. During fasting or low carbohydrate diet, glycerol 3-phosphate is generated by another metabolic pathway called glyceroneogenesis which uses precursors other than glucose. Glyceroneogenesis is considerably important because it is the dominant pathway to generate lipids during fasting or starvation. Not only it produces lipids for the organism but it also regulates lipid levels in the cell.〔 Glyceroneogenesis involves re-esterification of fatty acids to generate triglycerides. In other words, it can regulate fatty acid concentration in the cytosol. Strong activity in glyceroneogenesis will induce the re-esterification of fatty acid which will result in decrease of fatty acid concentration in the cytosol. Therefore, glyceroneogenesis is significantly related to lipid control of mammals. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Glyceroneogenesis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.