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HGSNAT : ウィキペディア英語版
HGSNAT


Heparan-α-glucosaminide ''N''-acetyltransferase (also called "acetyl-CoA:heparan-α-D-glucosaminide ''N''-acetyltransferase" and "acetyl-CoA:alpha-glucosaminide ''N''-acetyltransferase") is an enzyme that in humans is encoded by the ''HGSNAT'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=138050 )
In enzymology, this enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. It is catalysed in the chemical reaction:
:acetyl-CoA + heparan sulfate α-D-glucosaminide \rightleftharpoons CoA + heparan sulfate N-acetyl-α-D-glucosaminide
This enzyme participates in glycosaminoglycan degradation and glycan structures degradation. Mutations in the gene encoding this enzyme cause mucopolysaccharidosis IIIC.〔
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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