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HIP2
Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the ''UBE2K'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3093 )〕 The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.〔 == Interactions ==
HIP2 has been shown to interact with Huntingtin〔 and RNF2.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「HIP2」の詳細全文を読む
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