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・ Hla Myint Swe (artist)
・ Hla Pe
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・ Hla Tun
・ HLA-A
・ HLA-A*02
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・ HLA-A10
・ HLA-A11
・ HLA-A19
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・ HK-SF Ocean Film Festival
HK1
・ HK119
・ HK119 (album)
・ HK2
・ HK2 DI Kernel
・ HK3
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・ HKA
・ HKA test
・ Hka-u-in
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HK1 : ウィキペディア英語版
HK1

Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the ''HK1'' gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. (by RefSeq, Apr 2009 )〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3098 )
== Structure ==

HK1 is one of four highly homologous hexokinase isoforms in mammalian cells.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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