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・ HLA-B67
・ HLA-B7
・ HLA-B70
・ HLA-B73
・ HLA-B75
・ HLA-B77
・ HLA-B78
・ HLA-B8
・ HLA-B81
・ HLA-C
・ HLA-Cw*16
・ HLA-Cw4
・ HLA-Cw7
・ HLA-DM
・ HLA-DMA
HLA-DMB
・ HLA-DO
・ HLA-DOA
・ HLA-DOB
・ HLA-DP
・ HLA-DPB1
・ HLA-DQ
・ HLA-DQ1
・ HLA-DQ2
・ HLA-DQ3
・ HLA-DQ4
・ HLA-DQ5
・ HLA-DQ6
・ HLA-DQ7
・ HLA-DQ8


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HLA-DMB : ウィキペディア英語版
HLA-DMB

HLA class II histocompatibility antigen, DM beta chain is a protein that in humans is encoded by the ''HLA-DMB'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3109 )
== Function ==

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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