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HLA-DQ7 (DQ7) is an HLA-DQ serotype that recognizes the common HLA DQB1 *0301 and the less common HLA DQB1 *0304 gene products. DQ7 is a form of 'split antigen' of the broad antigen group DQ3 which also contains DQ8 and DQ9. DQ7 is linked by haplotype to a number of DQA1 (DQ alpha chain) genes, producing in cis-haplotype form, a large number of DQ αβ isoforms. These DQ alpha chains are also known to form transhaplotype isomers with other HLA-DQ. DQ7 is linked to the following alpha chains genes (DQA1 *) * 03 - *0301, *0302, *0303 * 0401 * 0505 * 0601 ==Serology== Serotyping efficiency. The serotyping efficiency of DQ7 toward DQB1 *0301 is reasonably good, but still results in some false negatives, for *0304 the typing efficiency is poor and cross-reaction with DQ8 is relatively high. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「HLA-DQ7」の詳細全文を読む スポンサード リンク
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