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HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western Europeans. Genes between B8 and DR3 on this haplotype are frequently associated with autoimmune disease. Type 1 diabetes mellitus is strongly associated with HLA-DR3 or HLA-DR4. ==Serology== Some DR3 also react with HLA-DR17 and/or HLA-DR18. The DRB1 *0304 primarily reacts with DR3. The serotypes of *0305, *0306, *0308 to *0331 are unknown. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「HLA-DR3」の詳細全文を読む スポンサード リンク
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