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HLA-DR51 is a HLA-DR serotype that recognizes the antigens encoded by the minor DR locus HLA-DRB5. DRB3, DRB4, and DRB5 are minor DR beta encoding loci, they have been recognized as having distinct evolution. having diverged from DRB1 approximately 4 million years ago. DRB5 locus is only apparent in a small subset of DR haplotypes, and most individuals lack DRB5. ==Alleles== DRB5 * is subdivided into two allele groups, DRB5 *01 and DRB5 *02. B5 *01 encodes 14 alleles and 11 isoforms. B5 *02 encoded 4 alleles that can generate 4 isoforms. Only 3 of these have been surveyed by serotyping. There are numerous null genes at this locus. DRB5 *01 allele group * 14 Alleles: 11 proteins, 2 Nulls * DR51 Serotype: *0101, *0102 * Serotype unknown: *0103 to *0107, *0109, *0110 to *0113 * Nulls: *0108N, *0110N DRB5 *02 allele group * 4 Alleles: 4 proteins * DR51 Serotype: *0202, * Serotype unknown: *0203 to *0205 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「HLA-DR51」の詳細全文を読む スポンサード リンク
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