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Words near each other
・ HNoMS Viking (1891)
・ HNoMS Æger
・ HNoMS Æger (1894)
・ HNoMS Æger (1936)
・ HNoMS Ørnen
・ HNoMS Ørnen (1829)
・ HNoMY Norge
・ Hnonae
・ Hnoss
・ HNP
・ HNRNPA0
・ HNRNPC
・ HNRNPL
・ HNRNPLL
・ HNRNPR
HNRPA2B1
・ HNRPA3
・ HNRPAB
・ HNRPD
・ HNRPDL
・ HNRPF
・ HNRPH1
・ HNRPH2
・ HNRPH3
・ HNRPK
・ HNRPU
・ HNRPUL1
・ HNS
・ HnS
・ HNS Convention


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HNRPA2B1 : ウィキペディア英語版
HNRPA2B1

Heterogeneous nuclear ribonucleoproteins A2/B1 is a protein that in humans is encoded by the ''HNRNPA2B1'' gene.
== Function ==

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3181 )
HnRNPA2B1 is an autoantigen in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and mixed connective tissue disease. When referred to as an autoantigen, hnRNPA2B1 is also known as RA33.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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