翻訳と辞書 ・ Homer, Indiana
・ Homer, Kansas
・ Homer, Louisiana
・ Homer, Michigan
・ Homer, Minnesota
・ Homer, Nebraska
・ Homer, New York
・ Homer, New York (disambiguation)
・ Homer, Ohio
・ Homer, Shropshire
・ Homer, Texas
・ Homer, Wisconsin
・ Homer-Center Junior/Senior High School
・ Homer-Center School District
・ Homer-Lovell House
・ HOMER1
・ HOMER2
・ HOMER3
・ Homerazzi
・ HomeRF
・ Homeric (disambiguation)
・ Homeric Greek
・ Homeric Hymns
・ Homeric Prayer
・ Homeric Question
・ Homeric scholarship
・ Homeric simile
・ Homeridae
・ Homerites
・ Homerland
|
|
HOMER1
Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the ''HOMER1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9456 )〕 Other names are Vesl and PSD-Zip45.
== Structure ==
Homer1 protein has an N-terminal EVH1 domain, involved in protein interaction, and a C-terminal coiled-coil domain involved in self association. It consists of two major splice variants, short-form (Homer1a) and long-form (Homer1b and c). Homer1a has only EVH1 domain and is monomeric while Homer1b and 1c have both EVH1 and coiled-coil domains and are tetrameric. The coiled-coil can be further separated into N-terminal half and C-terminal half. The N-terminal half of the coiled-coil domain is predicted to be a parallel dimer while the C-terminus half is a hybrid of dimeric and anti-parallel tetrameric coiled-coil. As a whole, long Homer is predicted to have a dumbbell-like structure where two pairs of EVH1 domains are located on two sides of long (~50 nm) coiled-coil domain.〔 Mammals have Homer2 and Homer3, in addition to Homer1, which have similar domain structure. They also have similar alternatively spliced forms.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「HOMER1」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|