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HQA : ウィキペディア英語版
Homoquinolinic acid

Homoquinolinic acid (HQA) is a potent excitotoxin which is a conformationally-restricted analogue of ''N''-methyl-D-aspartate (NMDA) and a partial agonist of the main/glutamate site of the NMDA receptor, with some selectivity for NR2B subunit-containing receptors. It is approximately equipotent to NMDA and about five times more potent than quinolinic acid as an agonist of the NMDA receptor. HQA has also been found to label a novel, yet uncharacterized binding site, which can be distinguished from the NMDA receptor with the use of 2-carboxy-3-carboxymethylquinoline (CCMQ), a selective ligand of the uncharacterized site.
==See also==

* Aspartate
* Ibotenic acid
* Tetrazolylglycine

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Homoquinolinic acid」の詳細全文を読む



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