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・ Haeju
・ Haeju Airport
・ Haeju Chongnyon Station
・ Haeju Stadium
・ Haeke language
・ Haela Brightaxe
・ Haelen
・ Haelogo Airport
・ Haely Jardas
・ Haem carrier protein - HCP1
・ Haem peroxidase
・ Haemabasis
・ Haemaccel
・ Haemachola
・ Haemactis
Haemadin
・ Haemadipsa
・ Haemadipsa picta
・ Haemadipsidae
・ Haemagglutination activity domain
・ Haemagglutinin-esterase fusion glycoprotein
・ Haemagogus
・ Haemal arch
・ Haemal nodes
・ Haemalea
・ Haemamoeba
・ Haeman Chatemee
・ Haemangela
・ Haemanota
・ Haemanota abdominalis


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Haemadin : ウィキペディア英語版
Haemadin

In molecular biology, haemadin is an anticoagulant peptide synthesised by the Indian leech, ''Haemadipsa sylvestris''.
It adopts a secondary structure consisting of five short beta-strands (beta1-beta5), which are arranged in two antiparallel distorted sheets formed by strands beta1-beta4-beta5 and beta2-beta3 facing each other. This beta-sandwich is stabilised by six enclosed cysteines arranged in a (3-5, 4-6 ) disulfide pairing resulting in a disulfide-rich hydrophobic core that is largely inaccessible to bulk solvent. The close proximity of disulfide bonds () and () organises haemadin into four distinct loops. The N-terminal segment of this domain binds to the active site of thrombin, inhibiting it.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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