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Holoendemic A disease is holoendemic when essentially every individual in a population is infected.〔(【引用サイトリンク】title=Holoendemic definition )〕 As the disease is ubiquitous, the young are more likely to express pathogenic responses, whilst the older hosts will carry the disease asymptomatically, or with reduced damage, due to adaptive immunity.〔〔 Note:"In the study area, like other holoendemic areas, youth is a risk factor for malaria. In comparison, adults in such areas have acquired permunition and can more readily resist infection and tolerate various symptoms associated with malaria."〕 Examples of this holoendemic pattern are seen with malaria in areas of sub-saharan Africa (where 75% of the deaths are in children under 5) and trachoma in areas of Saudi Arabia. ==References== 〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Holoendemic」の詳細全文を読む
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