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|Section2= }} Homosalate is an organic compound used in some sunscreens. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Contained in 45% of U.S. sunscreens, it is used as a chemical UV filter.〔(Homosalate ), ChemIDplus〕 The salicylic acid portion of the molecule absorbs ultraviolet rays with a wavelength from 295 nm to 315 nm, protecting the skin from sun damage. The hydrophobic cyclohexanol portion provides greasiness that prevents it from dissolving in water. ==Safety== Similar to other UV filter compounds, more homosalate is absorbed into the stratum corneum of the face (25% of applied dose) versus back of volunteers.〔() Benson et al., 2005〕 Homosalate has been identified as an antiandrogen ''in vitro'',〔() Ma et al., 2003〕 as well as having estrogenic activity toward estrogen receptors α,〔() Gomez et al., 2005〕 and general ''in vitro'' estrogenic activity.〔() Schlumpf et al., 2004〕 Homosalate has been shown to be an antagonist toward androgen and estrogen receptors ''in vitro''.〔() Schreurs et al., 2005〕 There is also heavy evidence that homosalate, (and other UV filters) can break down into more toxic products.〔() Klimova et al., 2013. Current problems in the use of organic UV filters to protect skin from excessive sun exposure. Acta Chimica Slovaca, 6(1):82—88, 〕 No evidence of toxicity or side effects have been documented ''in vivo''. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Homosalate」の詳細全文を読む スポンサード リンク
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