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Homotaurine : ウィキペディア英語版
Homotaurine

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Homotaurine (3-amino-1-propanesulfonic acid (3-APS) or tramiprosate (INN)) is a synthetic organic compound. It is analogous to taurine, but with an extra carbon in its chain. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant.
Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.〔(【引用サイトリンク】 date = November 1, 2007 )〕〔(【引用サイトリンク】title=Drugs In Clinical Trials : Alzhemed )
Homotaurine is a zwitterion at neutral pH.

==See also==

* Acamprosate

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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