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Hwp1 is a protein (glycoprotein) located on the surface of an opportunistic polyphenic fungus called ''Candida albicans''. Hwp1 is an acronym that stands for Hyphal wall protein 1. This "hyphal" denomination is due to Hwp1 appears exclusively on the surface of a projection called hyphae that emerges from the surface of this fungus. File:C albicans budding2.jpg|Candida Albicans Yeast forms (round-to-oval) File:C albicans germ tubes.jpg|Candida Albicans Hyphal forms (filamentous projections called hyphaes emerging from round-to-oval forms) Hwp1 is particularly important because it is a substrate of mammalian transglutaminase. This transglutaminase ability has two implications, one (in fungus pathogenicity) proved, and the other (in food proteins potential pathogenicity) hypothetical. == Fungus pathogenicity == Hwp1 has been proved to be involved in oral candidiasis. Candida albicans Hwp1 allows through the use of transglutaminase from the host (human beings, for example) adhere to human epithelial cells with the strength of a covalent bond (isopeptide bond to be precise) (the same strength in which human body proteins are built). This ability is highly related with ''Candida albicans'' being the prevalent Candida species in all types of candidiasis. Other candida species don't have the Hwp1 protein. File:Esophageal candidiasis (2) PAS stain.jpg|Micrograph of esophageal candidiasis showing hyphaes 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hwp1」の詳細全文を読む スポンサード リンク
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