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Hydroalkoxylation is a chemical reaction that combines alcohols with alkenes or alkynes. The process affords ethers. The reaction converts alkenes to dialkyl or aryl-alkyl ethers: :R'OH + RCH=CH2 → R'OCH(R)-CH3 Similarly, akynes are converted to vinyl ethers: :R'OH + RC≡CH → R'OC(R)=CH2 As shown, the reaction follows the Markovnikov rule. The process exhibits good atom-economy in the sense that no byproducts are produced. The reaction is catalyzed by bases and also by transition metal complexes.〔Alonso, F., Beletskaya, I. P., Yus, M., "Transition-Metal-Catalyzed Addition of Heteroatom-Hydrogen Bonds to Alkynes", Chemical Reviews 2004, volume 104, 3079. 〕 Usually symmetrical ethers are prepared by dehydration of alcohols and unsymmetrical ethers by the Williamson ether synthesis from alkyl halides and alkali metal alkoxides.〔Wilhelm Heitmann, Günther Strehlke, Dieter Mayer "Ethers, Aliphatic" ''Ullmann's Encyclopedia of Industrial Chemistry'' 2002, Wiley-VCH, Weinheim. 〕 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hydroalkoxylation」の詳細全文を読む スポンサード リンク
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