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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Hyperproinsulinemia ： ウィキペディア英語版 Hyperproinsulinemia Hyperproinsulinemia is a disease where insulin is not sufficiently processed before secretion and immature forms of insulin make up the majority of circulating insulin immunoreactivity in both fasting and glucose-stimulated conditions (insulin immunoreactivity refers to all molecules detectable by an insulin antibody, i.e. insulin, proinsulin, and proinsulin-like material). The term is composed of ''hyper'' - high, ''proinsulin'' - immature insulin molecule, and ''-emia'' - blood condition. Hyperproinsulinemia is more frequent in type 2 diabetes. It has been attributed to either a direct β-cells defect or an indirect effect of cell dysregulation under sustained elevated blood glucose (hyperglycemia). Some alleles of insulin can cause hyperproinsulinemia (see table 2: (monogenic forms of type 1 diabetes, INS (insulin) ). For a more detailed descriptions of the insulin gene variations leading to hyperproinsulinemia see NCBI's (OMIM 176730 ) ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hyperproinsulinemia」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.