|
Hyperthecosis is hyperplasia of the theca interna of the ovary.〔Taber's Cyclopedic Medical Dictionary 21st Edition〕 It is when an area of luteinization occurs along with stromal hyperplasia. The luteinized cells produce androgens, which may lead to hirsutism and virilization (or masculinization).〔Stead, Stead, Kaufman, Suarez (2009). First Aid for the Obstretrics & Gynecology Clerkship - Second Edition. McGraw-Hill〕 == See also == *Sexual differentiation *Secondary sex characteristics *Ambiguous genitalia *Androgen *Clitoromegaly *Hirsutism The term hyperthecosis refers to the presence of nests of luteinized theca cells in the ovarian stroma due to differentiation of the ovarian interstitial cells into steroidogenically active luteinized stromal cells. These nests or islands of luteinized theca cells are scattered throughout the stroma of the ovary, rather than being confined to areas around cystic follicles as in the polycystic ovary syndrome (PCOS). The result is greater production of androgens. The clinical features of hyperthecosis are similar to those of PCOS. However, women with hyperthecosis often have more markedly elevated testosterone, more hirsutism, and are much more likely to be virilized.〔http://www.uptodate.com/contents/ovarian-hyperthecosis〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Hyperthecosis」の詳細全文を読む スポンサード リンク
|